AFCON 2025-2026 Quarterfinals Betting Guide: Check Out the Best Predictions, Odds & Bets

This edition of the African Cup of Nations is proving to be one of the most exciting in years. From ‘human statue’ fans that have all eyes on them to surprising results and favorites limping to wins in the last 16, the Africa Cup of Nations quarterfinals promise more drama than ever. BetPlays’ AFCON quarterfinals betting guide arrives just in time, providing our readers with key insights into the round of last eight.

Canadian bettors looking to bet on AFCON should do proper research before wagering on this stage of the tournament. With our AFCON match previews, they should be able to get a clear idea of what might happen and find the AFCON best bets all in one place. Read on for the latest AFCON odds for the quarterfinals and previews for the upcoming clashes.

AFCON Quarterfinals – What’s at Stake?

If you’re from Africa and you love football, everything. The Africa Cup of Nations knockout stage separates the contenders from pretenders, and clears the air over the top favorites. Unlike other competitions, the AFCON quarterfinals usually feature tight games with few goals, and most matches are decided by small teams.

With the African football crown at stake, AFCON predictions today can be a real challenge. Teams are naturally cautious at this stage, so more often than not, the AFCON quarterfinals are a battle of wits. Most teams deploy a tactical approach, which opens up AFCON betting value in unders.

Of course, moneylines, handicaps, and even team/player props are all part of the action. The list of BetPlays AFCON betting markets is long and comes attached to great odds, which is why we strongly recommend players to read our AFCON match previews.

AFCON Quarterfinal Match Schedule

The AFCON quarterfinals fixtures are set, and it’s time for teams to prove their mettle. Some have struggled to get to this point, others have breezed. Regardless, it’s what you do on the Africa Cup of Nations quarterfinals that counts. The stakes are very high in this regard, and with the proud AFCON crown at stake, all teams should be on their highest level.

Here’s the AFCON match schedule for the ¼ finals:

Quarterfinal Match Previews & Betting Tips

With the schedule set, let’s take a look at all quarterfinal clashes schedule for tomorrow and the day after. We’ll cover each team’s form, key factors and possible outcomes, as well as smart betting angles.

Mali vs Senegal – AFCON Match Previews & Prediction

The first one of our AFCON quarterfinals betting previews is the match between Mali and Senegal in Tangiers. It kicks off at 17:00 (CET) tomorrow, and pits together two fierce rivals on the big stage.

Senegal has the star power and is more successful in the 40 duels against Mali in international football. The aging team entered the Cup of Nations outside of the top three favorites with odds that provided real value.

So far, Senegal has had the better tournament, and is the clear favorite in AFCON quarterfinals betting previews. The Lions of Teranga enter the duel with confidence, as Mali barely reached the last 16 with four draws in the group stage.

However, the Eagles proved capable of beating bigger teams with a penalty shootout victory against Tunisia. The team’s reliance on draws isn’t pure luck. It’s a cautious approach that might lead to another draw, which increases the chances for the underdog Mali to win on penalties again.

Regardless, the match against Senegal is a huge step up in quality. Most Africa Cup of Nations betting tips suggest a win for the Lions, ending Mali’s scrappy tournament.

Cameroon vs Morocco – AFCON Match Preview & Prediction

While all AFCON match previews attract a lot of attention, the derby will be played in Rabat on Friday (20:00 CET) between Cameroon and Morocco. The latter host the tournament and will be looking to secure a win against a Cameroon side that may prove tricky.

Morocco was and still is among the bookie’s favorites to win the Africa Cup of Nations. While the team has had a solid run so far, it hasn’t been as great as many hoped. That’s reflected in the AFCON odds for this match, which will prove even more challenging as Morocco has never beaten Cameroon in this competition.

Morocco got to the AFCON quarterfinals with a 1-0 win against Tanzania. It was an unnerving match for the hosts who are looking to bring the Cup of Nations home after 50 years. While the team has the quality to succeed, the win against Tanzania and draw against Mali in the group stage have raised some concerns.

Despite all the controversy, Cameroon has managed the tournament well so far. It beat South Africa 2-1 in the last 16 in a nervy finish. The team doesn’t score a lot of goals, and this will reflect in the AFCON quarterfinals betting markets such as totals.

Expect a close match with goals on both sides, and possibly under 3.5 goals. Goalscorer soccer betting props are also a good idea. Brahim Diaz leads the tournament in scoring, and he might be on point again in the quarterfinals.

Algeria vs Nigeria – AFCON Match Preview & Prediction

Algeria and Nigeria are in red-hot form, and the winner has a chance to go all the way. Algeria’s narrow victory against D.R. Congo brought the team to the quarterfinals, while Nigeria blitzed Mozambique 4-0.

Despite these results, it will be a tough AFCON quarterfinals betting showdown. Algeria has won the last three match-ups. The team has scored eight goals so far to Nigeria’s twelve in four matches. Nigeria boasts arguably the strongest attack at the tournament, with Victor Osimhen and Ademola Lookman leading the line.

Over 2.5 goals looks like a solid and valuable pick for this match. Algeria has nothing to lose after crashing out in group stage the last two AFCON’s, while Nigeria is aiming high. Both teams will be looking to score early and go for another goal, backing up the 2.5 line.

Egypt vs Ivory Coast – AFCON Match Previews & Prediction

Egypt was widely touted as the favorite for the AFCON title prior to the tournament together with hosts Morocco. Mohamed Salah’s team wasn’t impressive in the group stages, but will be looking to kick a few gears up a notch against Ivory Coast in the quarters.

The last time these teams met was in the 2021 edition of the tournament, where Egypt narrowly won on penalties in the round of 16. The Pharaohs are the most successful team in the Africa Cup of Nations with a record seven titles. If anyone knows how to win knockout rounds, it’s them.

Things won’t come easy against Ivory Coast. The team won dominantly against Burkina Faso 3-0 in the round of 16, while Egypt struggled to a 3-1 win in extra time against Benin.

Egypt has scored only one goal in the first half this tournament. Ivory Coast is in great goalscoring form, and with Sebastian Haller back from a ban, they might take the lead first. Canadian bettors should also take a look at goalscorers, including Mo Salah. The match will most likely be tight, so a penalties clash may be on the cards, too.

AFCON Quarterfinal Betting Tips – Strategy & Advice

There are several Africa Cup of Nations betting tips bettors should follow to maximize returns. First up is to bet responsibly. Manage your bankroll, set a bet size that you can afford to lose, and don’t overspend. These are the main pillars of responsible gambling every bettor should consider before they bet on AFCON.

Don’t overbet favorites. No matter how high their AFCON odds are, you should consider the underdog’s chances, as favorites don’t always win.

Instead of match winners, bettors from Canada may opt out for the to qualify market. The odds might be lower, but this market works well on parlays, where odds combine for a better payout.

Consider unders AFCON quarterfinals betting, as these matches are tactical in nature and often have fewer goals. Analyzing each team’s goalscoring form will show you if there’s value in the unders.

BetPlays – the Best Place to Bet on AFCON Quarterfinals

With the AFCON quarterfinals betting odds already live as the matches near, bettors should explore BetPlays’ Africa Cup of Nations hub. The quarterfinals provide plenty of fixed odds and live betting opportunities, with detailed stats and coverage of all the upcoming matches.

BetPlays’ Africa Cup of Nations odds offer a strong opportunity to make profit with the right approach and a solid betting strategy. Check out the latest AFCON match previews and place your wagers at BetPlays today.